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Posts tagged with "Academia (vs. Industry)"

  • Academia (vs. Industry)

    More Hot Air From Me on Screening

    After yesterday’s post on pathway patents, I figured that I should talk about high-throughput screening in academia. I realize that there are some serious endeavors going on, some of them staffed by ex-industry people. So I don’t mean to come across as thinking that academic screening is useless, because it certainly isn’t. What i… Read More
  • Academia (vs. Industry)

    Competing (And Competing Unethically?)

    Sean Cutler, a biologist at UC-Riverside, is the corresponding author of a paper in a recent issue of Science. That’s always a good thing, of course, and people are willing to go to a lot of trouble to have something like that on their list of publications. But Cutler’s worried that too many scientists, especially… Read More
  • Academia (vs. Industry)

    Poor Equipment Revisited

    A colleague came by a while ago and said “You know, the comments to that last post of yours are in danger of turning into Monty Python’s Four Yorkshiremen sketch“. At the moment, things are running about 50/50 between the “lack of equipment teaches you skills” and “lack of equipment wastes your time” camps. Read More
  • Academia (vs. Industry)

    The Perils of Poor Equipment

    The late Peter Medawar once wrote about resources and funding in research, and pointed out something that he thought did a lot more harm than good: various romantic anecdotes of people making do with ancient equipment, of great discoveries made with castoffs and antiques. While he didn’t deny that these were possible, and admitted that… Read More
  • Academia (vs. Industry)

    More Than This

    Science is taking a look at the 1991 members of Yale’s Molecular Biology and Biophysics PhD program. The ostensible focus of the article is to see what the effect of flat federal research funding has been on young potential faculty members, but there’s a lot more to pick up on than that. The first thing… Read More
  • Academia (vs. Industry)

    Lowe’s Law of Diurnal Distribution

    Here’s an appropriate topic for a Friday, although at first many of you may think I’ve lost my mind. What would happen if you combed the full text of the experimental sections of the chemistry journals, looking for how long people ran their reactions? I’m pretty sure that I know what you’d see: there would… Read More
  • Academia (vs. Industry)

    Getting To Lyrica

    There’s an interesting article in Angewandte Chemie by Richard Silverman of Northwestern, on the discovery of Lyrica (pregabalin). It’s a rare example of a compound that came right out of academia to become a drug, but the rest of its story is both unusual and (in an odd way) typical. The drug is a very… Read More
  • Academia (vs. Industry)

    Scrape Off Some Attitude

    There is a pecking order in chemistry. That’s because there’s one everywhere. If it’s a human endeavor, staffed by humans, you’re going to have hierarchies, real and perceived – who you did a post-doc with, what huge company you’re a big wheel in. But that doesn’t mean that we have to bow down to them… Read More
  • Academia (vs. Industry)

    Ugly, But Useful

      I also mentioned recently that I’d come across a good example of an academic compound with interesting activity but no chance of being a drug. Try this one out, from Organic Letters. Yes, there aren’t many other compounds that do what this one does (inhibit the production of TNF-alpha). And no, it’s not going… Read More
  • Academia (vs. Industry)

    Drugs From Where?

    The mention of tropical diseases here the other day turns out to be timely, since the latest Nature has several articles on various ways for industry and academia to partner on attacking these. Some adjustments are needed every time you try this sort of thing, naturally. I particularly enjoyed this article. Here’s a sample: “. Read More
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