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  • Cyclodextrin’s Day in the Sun

    Under the “Who’da thought?” category, put this news about cyclodextrin. For those outside the field, that’s a ring of glucose molecules… Read More
  • The Latest Sirtuin Controversy

    As promised, today we have a look at a possible bombshell in longevity research and sirtuins. Again. This field is going to make a pretty interesting book at so… Read More
  • Big Sirtuin News

    This will be the subject of a longer post tomorrow, but I wanted to alert people to some breaking news in the sirtuin/longevity saga. It now appears that the or… Read More
  • Merck, RNAi, Alnylam, And So On

    And while we’re on the topic of Merck, I note that they’re closing their RNAi facility in Mission Bay, the former Sirna. That was a pretty big deal… Read More
  • Bait And Switch For Type B GPCRs

    You hear often about how many marketed drugs target G-protein coupled receptors (GPCRs). And it’s true, but not all GPCRs are created equal. There’s… Read More
  • The Histamine Code, You Say?

    I’ve been meaning to link to John LaMattina’s blog for some time now. He’s a former R&D guy (and author of Drug Truths: Dispelling the My… Read More
  • The Uses of Disorder

    We spend a lot of time thinking about proteins in this business – after all, they’re the targets for almost every known drug. One of the puzzling th… Read More
  • Garage Biotech: The Book

    I haven’t read it yet, but there’s a new book on the whole “garage biotech” field, which I’ve blogged about hereand here. Biopunk… Read More
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