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Posts tagged with "Biological News"

  • Biological News

    Farewell to Bioinformatics

    Here are some angry views that I don’t necessarily endorse, but I can’t say that they’re completely wrong, either. A programmer bids an angry farewell to the bioinformatics world: Bioinformatics is an attempt to make molecular biology relevant to reality. All the molecular biologists, devoid of skills beyond those of a laboratory… Read More
  • Biological News

    Is Obesity An Infectious Disease?

    Like many people, I have a weakness for “We’ve had it all wrong!” explanations. Here’s another one, or part of one: is obesity an infectious disease? During our clinical studies, we found that Enterobacter, a genus of opportunistic, endotoxin-producing pathogens, made up 35% of the gut bacteria in a morbidly obese volunteer… Read More
  • Biological News

    Another Reactive Oxygen Paper

    Picking up on that reactive oxygen species (ROS) business from the other day (James Watson’s paper suggesting that it could be a key anticancer pathway), I wanted to mention this new paper, called to my attention this morning by a reader. It’s from a group at Manchester studying regeneration of tissue in Xenopus tadpoles, and… Read More
  • Biological News

    Reactive Oxygen Species Are Your Friends!

    The line under James Watson’s name reads, of course, “Co-discoverer of DNA’s structure. Nobel Prize”. But it could also read “Provocateur”, since he’s been pretty good at that over the years. He seems to have the right personality for it – both The Double Helix (fancy new edition there) and its notori… Read More
  • Biological News

    The Last Thing a Professor Wants to Hear

    This can’t be good. A retraction in PNAS on some RNA-driven cell death research from a lab at Caltech: Anomalous experimental results observed by multiple members of the Pierce lab during follow-on studies raised concerns of possible research misconduct. An investigation committee of faculty at the California Institute of Technology indicated… Read More
  • Biological News

    Sue the Nobel Committee. Yeah, That’ll Work.

    Rongxiang Xu is upset with this year’s Nobel Prize award for stem cell research. He believes that work he did is so closely related to the subject of the prize that. . .he wants his name on it? No, apparently not. That he wants some of the prize money? Nope, not that either. That he… Read More
  • Analytical Chemistry

    Picosecond Protein Watching

    We’re getting closer to real-time X-ray structures of protein function, and I think I speak for a lot of chemists and biologists when I say that this has been a longstanding dream. X-ray structures, when they work well, can give you atomic-level structural data, but they’ve been limited to static time scales. In the old… Read More
  • Biological News

    The 2012 Nobel In Chemistry. Yes, Chemistry.

    A deserved Nobel? Absolutely. But the grousing has already started. The 2012 Nobel Prize for Chemistry has gone to Bob Lefkowitz (Duke) and Brian Kobilka (Stanford) for GPCRs, G-protein coupled receptors. Update: here’s an excellent overview of Kobilka’s career and research. Everyone who’s done drug discovery knows what GPCRs are… Read More
  • Biological News

    ENCODE And What It All Means

    You’ll have heard about the massive data wave that hit (30 papers!) courtesy of the ENCODE project. That stands for Encyclopedia of DNA Elements, and it’s been a multiyear effort to go beyond the bare sequence of human DNA and look for functional elements. We already know that only around 1% of the human sequence… Read More
  • Biological News

    Databases and Money

    The NIH has been cutting back on its funding (via the National Libraries of Medicine) for a number of external projects. One of those on the chopping block is the Biological Magnetic Resonance Bank (BMRB), at Wisconsin: The BMRB mission statement is to “collect, annotate, archive and disseminate (worldwide in the public domain)” NMR data… Read More