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Posts tagged with "Biological News"

  • Biological News

    Rainbows and Fishing Expeditions

    I came across a neat article in Nature from a group working on a new technique in neuroscience imaging. They expressed an array of four differently colored fluorescent proteins in developing neurons in vivo, and placed them so that recombination events would scramble the relative expression of the multiple transgenes as the cell population expands. Read More
  • Biological News

    Avandia: Going Under for the Third Time?

    How many hits can a drug – or a whole class of drugs – take? Avandia (rosiglitazone) has been the subject of much wrangling about cardiovascular risk in its patient population of Type II diabetics. But there have also been scattered reports of increases in fractures among people taking it or Actos (pioglitazone), the other… Read More
  • Biological News

    A Real Genetic Headscratcher

    As you root through genomic sequences – and there are more and more of them to root through these days – you come across some stretches of DNA that hardly seem to vary at all. The hard-core “ultraconserved” parts, first identified in 2004, are absolutely identical between mice, rats, and humans. Our last common ancestor… Read More
  • Biological News

    What We Don’t Know About Enzymes

    There was an intriguing paper published earlier this month from Manfred Reetz and co-workers at the Max Planck Institute. It’s not only an interesting finding, but a good example of making lemonade from lemons. They were looking at an enzyme called tHisF, a thermostable beast from a marine microorganism that’s normally involved in hista… Read More
  • Alzheimer's Disease

    Checking The Numbers on the Alzheimer’s Test

    The news of a possible diagnostic test for Alzheimer’s disease is very interesting, although there’s always room to wonder about the utility of a diagnosis of a disease for which there is little effective therapy. The sample size for this study is smaller than I’d like to see, but the protein markers that they’re finding… Read More
  • Biological News

    Let Us Now Turn To the Example of Yo’ Mama

    Now we open the sedate, learned pages of Nature Methods, a fine journal that specializes in new techniques in molecular and chemical biology. In the August issue, the correspondence section features. . .well, a testy response to a paper that appeared last year in Nature Methods. “Experimental challenge to a ‘rigorous’ BRET analysis of GPCR… Read More
  • Biological News

    More Things Than Are Dreamt Of

    It’s useful to be reminded every so often of how much you don’t know. There’s a new paper in PNAS that’ll do that for a number of its readers. The authors report a new protein, one of the iron-sulfur binding ones. There are quite a few of these known already, so this wouldn’t be big… Read More
  • Biological News

    Visfatin: Real Or Not?

    A commentor to my Proteomics 101 post the other day brought up an important point: that before you can have a chance to figure out what a protein is doing, you have to know that it exists. Finding the darn things is no small job, since you’re digging through piles of chemically similar stuff to… Read More
  • Biological News

    It Went Up Instead of Down

    One of the things I like most about science is that you really don’t know what’s going to happen next. That’s especially true in the areas where things have just barely settled down. Before that, when a field is new, no one knows what to expect, so in a way there aren’t really any surprising… Read More
  • Biological News

    Peptides as Texts

    There’s a curious paper (subscriber-only link) in the latest Nature that’s getting some attention, titled “A linguistic model for the rational design of antimicrobial peptides”. For non-subscribers, here’s a synopsis of the work from the magazine’s news site. A group at MIT headed by Gregory Stephanopolous has be… Read More