Skip to Content
  • A New Bioorthogonal Reaction

    I wanted to mention a new bioorthogonal reaction that’s been reported from the Bertozzi lab at Stanford. This one is between N-oxides and diboron compound… Read More
  • The Sales Pitch Via the Literature

    In the past weeks, I’ve noticed a couple of papers using the HaloTag system for in vivo chemical biology. Here’s one on target ID (open access, subm… Read More
  • PROTAC Goes Small-Molecule

    Since I mentioned the Bradner lab’s protein-destruction technology recently, I should also highlight this recent paper from Craig Crews and co-workers. In… Read More
  • Targeting Proteins for Destruction

    Here’s an excellent new paper that’s appeared in the preprint area of Science, Science Express. Jay Bradner and co-workers at Harvard/Dana-Farber re… Read More
  • Controlling Proteins, One by One

    Here’s what looks like a very useful method for turning protein function on and off, reported in a new paper in Nature Chemistry. (This PDF link may work… Read More
  • Aileron and p53

    In the long-running saga of getting a stapled peptide to work as a drug, Aileron Therapeutics was last heard from raising money for their p53 candidate. Now com… Read More
Page 4 of 12« First...23456...10...Last »