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  • A Tour of the Outer Precincts

    You know, in an odd way, I’m actually more optimistic about drug discovery than I was a few years back. It’s due to the new tools that we have in mo… Read More
  • Experiments, Lots of Experiments

    Here’s a useful guide to setting up lots of experiments – which is something that you’d think we science types already would know how to do, b… Read More
  • Photoreactors For All

    I’ve been hearing about this for a while now, so I’m glad to link to the manuscript (open access, now with a working link!) on a new photoreactor t… Read More
  • Couple Your Primary Amines

    Here’s another neat carbon-carbon bond forming reaction (and no, we organic chemists just cannot get enough of these things). It’s from Mary Watson… Read More
  • The Chan-Lam Reaction, Tamed At Last

    Many synthetic organic chemists will be familiar with the Chan-Lam reaction, where an organoboronic acid or ester is reacted with an amine in the presence of a… Read More
  • Macrocycles For the Making

    I meant to write about this paper at the time, but there’s no harm in highlighting it now. A group at the University of Toronto reports a neat way to make… Read More
  • New Looks At Two Classic Reactions

    It’s hard to imagine a functional group that’s been more heavily studied than amides. They are, of course, the literal backbone of protein chemistry… Read More
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