Skip to Content

Posts tagged with "Chemical News"

  • Analytical Chemistry

    Triangulene, By Force

    The molecule on the right is triangulene, and it’s an odd one. You’d think at first that you could fill everything in with alternating double bonds, like a small piece of graphite or a bigger relative of anthracene, but when you try, you find that the geometry won’t let you. You’re either going to end… Read More
  • Chemical News

    How Not to Do It: TATP

    You may well have heard about an incident at the University of Bristol, where a student inadvertently prepared some triacetone triperoxide (TATP). That’s a substance that I definitely won’t work with, but I haven’t done an entry on it in that category because of its unfortunate significance. No one is going to make a batch… Read More
  • Chemical News

    Phil Baran Takes on the Crowd

    This should be interesting – Phil Baran of Scripps will be going on Reddit at 2 PM EST (update: looks like he’s already at it) to do one of their “Ask Me Anything” conversations. My own experiences taking questions there is colored by working in the pharma industry; as you’d imagine, a good number of… Read More
  • Chemical Biology

    More Spring-Loaded Reagents

    I wrote just about this time last year about a new “strain-release” bond forming reaction system from the Baran group at Scripps. Now they’ve got a good-sized paper in JACS with more reactions in that line, but be warned. If you hit “Print” on the Supporting Information file, you’d better have spare paper, becaus… Read More
  • Chemical News

    Allotropes, Allotropes Everywhere

    I’ve always liked allotropes, and I think that a lot of chemists do. The idea of the same pure element forming completely different materials (graphite and diamond, white phosphorus and red) is a vivid illustration of what chemical bonding and structure are all about. The subject is in the news as word has come of the… Read More
  • Chemical News

    Trifluoromethylate The Lot of ‘Em

    Here’s another one of those papers in the category of “reactions that medicinal chemists like”. It’s a new way to make trifluoromethyl amines, and it seems pretty versatile and tolerant of functionalized molecules. That’s a class of compound that traditionally has not been very much fun to make, and sometimes calls for… Read More
  • Chemical News

    Nitration Isn’t So Simple

    OK, let’s get physical organic here for a little while. For atat ose outside the field, physical organic chemistry is the branch that studies how and why the reactions of organic chemistry happen – the details of which bonds break and form, in what order, in what arrangement, where the atoms and electrons are moving and… Read More
  • Chemical News

    All Is Forgiven At 1000 Degrees

    I can’t say that I’ve ever done any flash vacuum pyrolysis, and I’ll bet that most chemists reading this haven’t, either. I’ve seen papers on it for many years, including some pretty unusual reactions, but it’s never been a tool that I’ve reached for. Here’s a new paper in the Journal of Organic Chemi… Read More
  • Chemical News

    David Weininger and Chemical Names

    David Weininger passed on last week, and you probably have to be into chemoinformatics for that name to immediately register. He came up with the SMILES notation for chemical structures, though, so that should make his contributions clear. Here’s an excellent appreciation by Anthony (“Ant”) Nicholls that will really give you a sen… Read More
  • Chemical News

    Chemical Storage, Good and Not So Good

    Back to science! I will admit that my Twitter feed is going to be rather more politicized than usual for some time to come, but this is not a political site, and thank God for that. I have to say, it certainly brings in the comments and the traffic, but that’s not my goal in life. Read More