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Posts tagged with "Chemical News"

  • Chemical News

    New Photochemistry, And Even Better

    I wanted to mention this excellent new paper on cross-coupling arylamine formation that’s come out in Science. It’s a collaboration between the Macmillan lab at Princeton, the Buchwald lab at MIT, and the Merck process chemistry group. That’s a lot of expertise among them, particularly in the fields of photoredox catalysis and ary… Read More
  • Academia (vs. Industry)

    Want Your Compounds Tested Against Pathogens For Free?

    I’d like to help publicize what seems like a very worthwhile effort, funded by the University of Queensland and the Wellcome Trust: the Community for Open Antimicrobial Drug Discovery (CO-ADD). Here’s a writeup on them in Nature – what they’re doing is taking compounds from all sources and screening them against panels of i… Read More
  • Chemical News

    Antibiotics From Scratch

    There’s a lot more antibiotic news to cover this week, and I thought I’d start out with some very high-level organic chemistry. This paper from the Myers lab at Harvard is really nice stuff: they’re looking at macrolide antibiotics (such as erythromycin) and trying to find ways to make large number of variations of them… Read More
  • Academia (vs. Industry)

    A Professor’s View On Drug Company Collaborations

    My post the other day on Phil Baran’s public-private funding ideas brought in a lot of comment. As usual, I encourage a look a the comments section if you’re interested in the topic, or any topic that comes up around here – a lot of people who know whereof they speak show up. But I… Read More
  • Chemical News

    Manure Is Organic, Let’s Not Forget

    Chemjobber put me on to this lawsuit filing, which is brought by the Organic Consumer’s Association versus The Honest Company. To decode all these, the OCA is an advocacy group (one of the most aggressive) for organic farming, and gets its funding both from its members and from the organic farming industry. You can pretty much fill… Read More
  • Biological News

    A New Natural Products Effort

    Since I mentioned natural products drug discovery the other day, I wanted to note that there’s a new effort at the NIH to screen samples. The CANVASS project is asking for pure isolated compound (not extracts), and will screen them across dozens of diverse cell assays, free of charge. The academic group that provides the… Read More
  • Analytical Chemistry

    Grinding Up The Leaves and Roots

    I’ve been meaning to write about this Stat profile of Jing-ke Weng at the Whitehead Institute, who’s searching for medicinally active compounds in exotic plants. That’s a field with a long and honorable history – some ferociously active compounds come from plant sources, and some terrific drugs have, too. But it’s been… Read More
  • Biological News

    The Myth of Ethidium Bromide

    Ethidium bromide is found in pretty much every molecular biology lab around. Ask most biologists about handling it, and you’re get a fearful expression and advice to use gloves, etc. That’s because the compound is used to make DNA fluoresce when running gels, and it does that by slipping neatly between the base pairs (intercalation)… Read More
  • Chemical News

    The Algorithms Are Coming

    I think that every synthetic organic chemist should take a look at this paper in Angewandte Chemie. It’s on the application of computer algorithms to planning synthetic routes, which is a subject that’s been worked on for fifty years or more – without, it has to be said, making too much of an impression on… Read More
  • Chemical News

    Deepfryer Cow Cow, Wahoo Zipzang

    So it turns out that the credit cards issued by the NIH Federal Credit Union have chemical structures all over them. Isn’t that a good thing, recognizing their scientific roots and all? Don’t you find these chemical structures meaningful and inspiring? Don’t they make you want to kick something? The graphic designers strike again. Read More