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  • A Ligand Efficiency Reply

    The inevitable reply to the Schulz paper on the validity of ligand efficiency measurements has appeared in ACS Medicinal Chemistry Letters. Sent in from a numbe… Read More
  • Photoredox Marches On

    I found this paper from the MacMillan group on photochemical decarboxylation pretty interesting, but I always find new ways to make carbon-carbon bonds worth re… Read More
  • Back Ordered, I’ll Bet

    I’ve actually never heard of “”, but a reader sent this interesting page along to me. So if you’re in the market for “ Read More
  • Is That Food or Not?

    Several people have written me after noticing this article on Taco Bell’s ingredients. ABC gave me a call, since their reporter remembered my take on the… Read More
  • Gitcher SF5 Groups Right Here

    I think that several of us in medicinal chemistry have been keeping our eyes out for a chance to work in a pentafluorosulfanyl (SF5) group. I know I have –… Read More
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