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  • Copper: A Gentleman’s Disagreement

    I was running a copper-catalyzed coupling reaction the other day when my summer intern asked me how it worked. I showed her the mechanism that the authors of th… Read More
  • New Tricks With Glassware

    Courtesy of Steve Ley’s group, here’s a lab trick I’d never come across before. They were trying to purify a nasty mixture of closely related isomers, and… Read More
  • DNA Forklifts, DNA Pliers

    Manipulating nanoscale objects is a very hot research area these days, but no one’s quite sure whether it should be called physics or chemistry. The single-at… Read More
  • Le Dernier Cri

    There are plenty of chemical reagents and reactions that go in and out of fashion over the years, and even entire elements. For the last couple of years, it’s… Read More
  • One For the Brave

    I was interested to see a recent paper in Organic Letters on a class of compounds I’d never seen before: 1,2-dihydro-1,2-azaborines. There’s the str… Read More
  • Ertl Wins: Down With Witchcraft

    As some had speculated, the Nobel in chemistry did take a turn toward physical chemistry this year, for the first time in some while. Gerhard Ertl has won for h… Read More
  • All Sorts of Holes

    One of the things I like most about science is how thoroughly you can be taken by surprise. A good check on a field’s vigor is whether or not its practitioner… Read More
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