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Posts tagged with "Chemical News"

  • Chemical News

    The Real Hazards of the Lab

    A run of bad accident news today, and all of the same kind. The Chemistry Blog has the story of a fatality in the labs at UCLA. The short and painful details are: inexperienced student, t-butyllithium, flammable clothing, and panic (as in not running toward the safety shower). This is very sad to hear about… Read More
  • Analytical Chemistry

    The Great Acetonitrile Shortage

    Now here’s a news item that I’m pretty sure you haven’t heard about unless you work in or near a laboratory. We’re in the middle of an extreme shortage of acetonitrile, a common solvent. This has been going on since back in the fall, but instead of gradually getting better, it’s been gradually getting worse: Read More
  • Chemical News

    Diversity-Oriented Synthesis: Oriented The Right Way?

    Ever hear of Diversity-Oriented Synthesis? It’s an odd bird. DOS tries to maximize the number of structures and scaffolds produced from a given synthetic scheme – to find the most efficient ways to populate the largest amount of chemical space. In a way, it’s the contrapositive of natural product synthesis, which focuses all its effort… Read More
  • Chemical News

    Short Items: Viral NMR, Alarming Rings, Cheap Reading, Etc.

    From PNAS, here’s an ingenious method that’s allowed NMR-based imaging of particles as small as viruses. I didn’t even think that this was possible – so now that it is, look for all kinds of variations on it over the next few years, as is the way of NMR techniques. Single-cell MRI? As the authors… Read More
  • Chemical News

    An Impressive Nanolist of Nanocitations

    Time for just a brief piece this morning, about a topic I’ve mentioned before which is getting more noticeable all the time. If you follow the papers coming out in the Journal of the American Chemical Society (known as “Jay-ay-cee-ess” or just plain “Jacks” to the working chemist), you’ve been seeing an awful lot… Read More
  • Chemical News

    Copper: A Gentleman’s Disagreement

    I was running a copper-catalyzed coupling reaction the other day when my summer intern asked me how it worked. I showed her the mechanism that the authors of the paper had proposed, but pointed out that it was mostly hand-waving. The general features are probably more or less right: the copper iodide presumably does form… Read More
  • Chemical News

    New Tricks With Glassware

    Courtesy of Steve Ley’s group, here’s a lab trick I’d never come across before. They were trying to purify a nasty mixture of closely related isomers, and found that the best chromatographic separation came from a long, long, run in ether/hexane. I’ve been in that situation myself, but it’s hard to have the patience to… Read More
  • Chemical News

    DNA Forklifts, DNA Pliers

    Manipulating nanoscale objects is a very hot research area these days, but no one’s quite sure whether it should be called physics or chemistry. The single-atom stuff (like the famous 1989 spelling of I-B-M using an early scanning tunneling microscope tip) would probably be the former, while moving whole molecules around would probably be the… Read More
  • Chemical News

    Le Dernier Cri

    There are plenty of chemical reagents and reactions that go in and out of fashion over the years, and even entire elements. For the last couple of years, it’s been gold – ten years ago, gold-catalyzed reactions were a backwater, and now they’re all over the literature. (Catalysts are the way to go; reactions that… Read More
  • Chemical News

    One For the Brave

    I was interested to see a recent paper in Organic Letters on a class of compounds I’d never seen before: 1,2-dihydro-1,2-azaborines. There’s the structure, in case that doesn’t immediately call something to mind. These things, which are isoelectronic with benzene, were made by the Liu group at Oregon. Their method (ring-closing me… Read More
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