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Posts tagged with "Chemical News"

  • Chemical News

    175 Times. And Then the Catastrophe.

    I noted this item over at C&E News today, a report on a terrible chemical accident at T2 Laboratories in Florida back in 2007. I missed even hearing about this incident at the time, but it appears to have been one of the more violent explosions investigated by the federal Chemical Safety and Hazard Board… Read More
  • Chemical News

    “Scratch and Sniff” Turns Into “Zap and React”

    Here’s an odd idea that might turn into something useful. A group at Berkeley (spanning both the chemistry and physics departments of Cal-Berkeley and the Lawrence labs) have reported a method for encapsulating organic molecules and releasing them inside a reaction when needed. What they do is form microcapsules, small polymer spheres, from b… Read More
  • Chemical News

    Another Iron Reaction Hits The Mat

    Beware of iron! That’s the lesson that’s being hammered home these days in synthetic chemistry. I wrote recently about the discovery that a series of iron-catalyzed couplings were actually being caused by trace amounts of copper compounds. Now there’s another re-examination of some similar iron couplings that were reported last ye… Read More
  • Chemical News

    Rings of the Future!

    Here’s an interesting paper that some of you may have seen in J. Med. Chem.: “Heteroaromatic Rings of the Future”. That’s an odd title, but an appropriate one. For the non-chemists in the crowd who made it to this paragraph, heteroaromatic rings are a very wide class of organic compounds. They’re flat cyclic structures… Read More
  • Chemical News

    Everything In Its Place

    Things are pretty quiet around the industry these days, so my blogging thoughts have been turning to Big General Problems. And here’s one that I know that people are working on, but which I think we as chemists are going to have to understand much better: localization. “Say what?” is the usual response to that… Read More
  • Chemical News

    The Further In You Go, The Bigger It Gets

    I had a printout of the structure of maitotoxin on my desk the other day, mostly as a joke to alarm anyone who came into my office. “Yep, here’s the best hit from the latest screen. . .I hear that you’re on the list to run the chemistry end. . .what’s that you say?” This… Read More
  • Chemical News

    Devils, Metals, and Details

    Organic synthesis as we know it can’t go on without metal-catalyzed bond-forming reactions. There are too many of them, and they’re just too useful. Palladium’s the workhorse, followed by copper, then you’ve got rhodium, nickel, and a host of others (gold’s been popular the last few years). We have a. . .fairly good id… Read More
  • Chemical News

    TMS Diazomethane: Update On a Fatality

    I’ve been contacted by several people over the last few weeks about the TMS diazomethane-linked fatality in Nova Scotia (first written about here). Many more details are emerging about the case, chief among them that the fume hoods in the lab were apparently down for maintenance during this time. Here’s a newspaper article that’s… Read More
  • Chemical News

    Writing With Triazoles

    I’ve written before about the copper-catalyzed triazole formation (often referred to as “click chemistry”). It’s turned into a very useful way to stick all sorts of molecules and structures together, and is showing up in materials science, biochemistry, organic synthesis and other fields. Now Fraser Stoddart’s lab has a new variation on t… Read More
  • Biological News

    The Motions of a Protein

    So, people like me spend their time trying to make small molecules that will bind to some target protein. So what happens, anyway, when a small molecule binds to a target protein? Right, right, it interacts with some site on the thing, hydrogen bonds, hydrophobic interactions, all that – but what really happens? That’s surprisingly… Read More