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Posts tagged with "Drug Industry History"

  • Drug Industry History

    Targets to Avoid (Or That We Wish We Had)

    A discussion with colleagues recently got me to wondering about this useful (albeit grim) question: what area of drug discovery over the last twenty years would you say has taken up the most resources and returned the least value? I’m thinking more of disease/therapeutic areas, but other nominations are welcome, of course. My own candidate… Read More
  • Chemical News

    Fifty Years of Med-Chem Molecules: What Are They Telling Us?

    I wanted to send people to this 50-year retrospective in J. Med. Chem.. It’s one of those looks through the literature, trying to see what kinds of compounds have actually been produced by medicinal chemists. The proxy for that set is all the compounds that have appeared in J. Med. Chem. during that time, all… Read More
  • Drug Industry History

    A Dish Best Served Cold

    And the well-known chem-blogger Milkshake knows how to serve it. See his latest post here. It doesn’t qiote make up for having one’s company bought out, having everyone moved and fired and hosed around, and having to go to court for the severance package that you were promised. . .but you have to take your… Read More
  • Drug Development

    GlaxoSmithKline Reviews the Troops

    Several readers sent along this article from the Times of London (via the Ottawa Citizen) on GlaxoSmithKline’s current research setup. You can tell that the company is trying to get press for this effort, because otherwise these are the sorts of internal arrangements that would never be in the newspapers. (The direct quotes from the… Read More
  • Business and Markets

    Chinese Pharma: No Shortage of Ambition, Anyway

    When does China take the next step in drug research? They already have a huge contract research industry, and they have branches of many of the major pharma companies. But when does a Chinese startup, doing its own research with its own people in China, develop its own international-level drug pipeline? (We’ll leave aside the… Read More
  • Business and Markets

    The Economics of the Drug Industry: Big Can’t Be Big Enough?

    I wanted to extract and annotate a comment of Bernard Munos’ from the most recent post discussing his thoughts on the industry. Like many of the ones in that thread, there’s a lot inside it to think about: (Arthur) De Vany has shown that the movie industry has developed clever tools (e.g., adaptive contracts) to… Read More
  • Drug Industry History

    Read the Comments

    Just wanted to point out to anyone who’s not reading the comments here that the ones to this post are of extremely high quality. If you want to hear the thoughts of a lot of intelligent, experienced people on what’s wrong with the drug industry and what might be done to fix it, have a… Read More
  • Alzheimer's Disease

    Bernard Munos Rides Again

    I’ve been meaning to link to Matthew Herper’s piece on Bernard Munos and his ideas on what’s wrong with the drug business. Readers will recall several long discussions here about Munos and his published thoughts (Parts one, two, three and four). A take-home message: So how can companies avoid tossing away billions on medicines tha… Read More
  • Business and Markets

    A Former Pfizer Executive Finally Trashes Pfizer’s Strategy

    A number of readers have noted this piece by John LaMattina in Nature Reviews Drug Discovery. He is, of course, a former head of R&D at Pfizer, which makes the title of the article something of an attention-getter: “The impact of mergers on Pharmaceutical R&D”. Pfizer, for those of you just returning from a near-lightspeed… Read More
  • Drug Industry History

    Merck Moving Research From Rahway?

    I’ve heard from more than one person that Merck has decided to move most discovery research out of Rahway (in favor of the former Schering-Plough site in Kenilworth). Details are welcome in the comments from those with better information. That news does bring on end-of-an-era feelings, since they’ve been doing medicinal chemistry in Rah… Read More