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  • Going After Ebola

    How small-molecule drugs fit into binding pockets in their targets is one of the central questions of medicinal chemistry. A new paper from a group at Oxford g… Read More
  • New Antibiotic Action

    I’m always happy to hear about new agents to treat gram-negative bacterial infections, especially after a stint working in antibiotic drug discovery mysel… Read More
  • Small Proteins: Into the Gap

    We medicinal chemists are used to thinking about small molecule drugs – it’s what we do. And we’re also comfortable with having a category in… Read More
  • Bacteria Can Make Tumors Worse

    Since the topic of bacteria effects on human disease came up here just the other day, I wanted to point out a new article that comes at this idea from a differe… Read More
  • Tagging Fungi For Destruction

    Fungal infections can be very bad news when they go beyond the get-something-from-the-drugstore stage. That fact that a drug as rough as amphotericin B is still… Read More
  • Where MRSA Came From

    OK, everyone recognizes the problem that we face with drug-resistant bacteria. MRSA (methicillin-resistant Staphylococcus aureus) is the most well-known variety… Read More
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