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Posts tagged with "Infectious Diseases"

  • Cardiovascular Disease

    Where’s the Combo?

    Gruntdoc wonders about why a particular combination therapy isn’t available yet. Skin infections with methacillin-resistant staphylococcus aureus (MRSA), which I hope I never come any closer to experiencing, are treated with one of several antibiotic combinations, but they’re all administered as separate drugs. The answer is what you mi… Read More
  • Infectious Diseases

    Fan Mail

    This is the first one of these I’ve had since I started blogging. It’s in response to this recent post, and I thought I’d celebrate by sharing it with everyone: “You are a shameful individual Mr. Lowe – to make a living in the pharmaceutical industry, whether past or present and then turn around and… Read More
  • Business and Markets

    Pfizer Opens Their Wallet – Again

    Well, as a comment to Tuesday’s post mentioned, no sooner do I talk about the antifungal market than Pfizer turns around and buys a company with a promising antifungal drug. Vicuron has concentrated on antiinfectives in general, which has been a rough place to be over the last ten years or so. Good ideas are… Read More
  • Infectious Diseases

    Fungal Problems

    You want a tough therapeutic area to work in? Try antifungals. There are plenty of problems that conspire to make it a real headache. For one, fungal infections have a way of binning themselves into two categories, marked “pretty trivial” and “pretty life-threatening.” Athlete’s foot is a good example of the first one… Read More
  • Infectious Diseases

    Dr. Rath Does What He Can

    There’s a doctor named Matthias Rath who for some years has been taking out big ads in the New York Times and the International Herald Tribune. Rath is a big proponent of megavitamin therapy for just about everything, and by some cosmic coincidence he also has a line of vitamins for sale. No doubt he… Read More
  • Infectious Diseases

    Vertex Turns Over a Winner

    Vertex announced some impressive clinical data against hepatitis C the other day, which has been a fine thing for their stock price. It looks to be a fine thing for people infected with hepatitis as well, with better results than the current interferon therapy in a much shorter time. I’d have to guess that the… Read More
  • Infectious Diseases

    Do It Again

    This is the 50th anniversary year of the announcement of Jonas Salk’s polio vaccine, as you’ve probably been noticing. There a new book out on the discovery, and plenty of newspaper and magazine articles. I’ll save comment on the vaccine (and Salk himself) for another time. What got me thinking was an incident during the… Read More
  • Infectious Diseases

    An Antiviral Example

    I mentioned yesterday that sometimes you can find an antiviral target that doesn’t depend on what the virus itself has to offer. As fate would have it, there are a few drugs coming along that use just such a mechanism against HIV. They’re based on their affinity toward a protein called CCR5, which sits straddling… Read More
  • Infectious Diseases

    Can Med-Chem Help With Bird Flu?

    If avian flu does gain a foothold in humans, what can drug companies do about it? (This should give you the latest headlines on the disease.) It’s definitely something to worry about. There hasn’t been a real rampager of a flu epidemic in a long time, and a pessimist would say that we’re overdue. The… Read More
  • Infectious Diseases

    Empty Shelves

    Yesterday I was writing about a proposal to encourage new antibiotics, partly by not putting so much effort into discouraging the use of the current ones. The economist who’s advocating this, Paul Rubin, also would like for the FDA to consider accelerating the approval process (and at the very least, not making it even harder… Read More