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  • Asking the Employees

    Every company that I’ve ever worked for has said that they want suggestions from the employees – some of them have been serious, and others were say… Read More
  • Five Tons of TiCl4

    I would definitely not want to be downwind of the release of five tons of titanium tetrachloride. This happened near Montreal over the weekend, and things seem… Read More
  • What Compound Will You Never Forget?

    While catching up on the literature today, I find that even now, thirty years later, I can’t look at a paper that uses 1,6-anhydroglucose (levoglucosan to… Read More
  • OK, You San Diego People

    I’ve already been hearing from people out on the West Coast about how it’s seventy-odd Fahrenheit out there. My first thought was “It’s… Read More
  • Tolerant Chemistry: Be Glad of It

    Like a lot of other scientists in the Northeast today, I’m getting things in the lab ready for me not being there tomorrow. (I just ran into a colleague w… Read More
  • Get Your Spirocyclic Compounds Here

    If you do early-stage medicinal chemistry, you’ll probably be interested in this overview of spirocyclic scaffolds. It has examples from the recent litera… Read More
  • Not So Scalable

    Unworkable compounds are one thing. Unworkable processes and reactions are just as big a problem, though. You don’t see as many paper proposing those as y… Read More
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