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Posts tagged with "Odd Elements in Drugs"

  • Cancer

    Arsenic, Patents, and the World

    As I was mentioning the other day, the latest issue of Nature Medicine has the details on a story that doesn’t, on the face of it, do the industry any credit. About twenty years ago, there were reports out of China that a solublized form of arsenic was very effective in treating acute promyelocytic leukemia… Read More
  • Odd Elements in Drugs

    My Shopping List

    Some time ago I wrote about some atoms that I wish I could use. There are still other molecular fragments that Nature has neglected to provide, though, and I’m adding to the wish list: First off, I’d like some groups that are plain linear spacers of different lengths. Ideally, we could stick these onto carbons… Read More
  • Drug Development

    Odd Elements in Drugs: Silicon

    Another chemical element that you don’t see much in pharmaceuticals is silicon. Hey, it’s right under carbon in the periodic table, and forms four tetrahedral bonds just like carbon does, so why not, eh? Now, if you’re like me, you grew up reading old science fiction stories that posited silicon-based life forms. That seemed prett… Read More
  • Odd Elements in Drugs

    Odd Elements in Drugs

    I had a question recently about why some chemical elements don’t appear much in pharmaceuticals. Boron was one example – the first boron-containing drug (Velcade, from Millennium) was approved just recently. But it hasn’t been for lack of trying. Starting in the 1980s, several drug companies took a crack at boronic acids as head g… Read More
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