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  • Ever Finer Splitting

    Charles Darwin once divided scientists into two types: “splitters” and “lumpers”. The splitters are the ones who keep finding finer dist… Read More
  • Three Not-So-Reproducible Papers

    You may well remember Amgen’s statement in 2012 about how many academic papers they were having trouble reproducing. Not everyone has taken it seriously,… Read More
  • Alkermes Hits a Wall in Depression

    In case you hadn’t seen it, CNS drug development recently did what it’s really good at doing: disappointing people late in the clinic. Alkermes had… Read More
  • Unpleasant Alzheimer’s News

    Here are a couple of new developments in Alzheimer’s and dementia – nothing encouraging, unfortunately. A new paper in JAMA Internal Medicine, from… Read More
  • Simulating the Brain. Sure Thing.

    My mention the other day of Japan’s Fifth Generation computer project prompted a reader to send along this link, which I thoroughly enjoyed. It concerns t… Read More
  • The Rising Placebo Effect

    The placebo effect has many interesting and annoying features, among them the way that it varies so much among different therapeutic areas. There is no placebo… Read More
  • Into the Numbers

    I want to recommend this analysis (at the Mind the Brain blog) of a new paper in PLOS Medicine. The paper is an analysis from a very large Swedish data set of p… Read More
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