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Posts tagged with "The Scientific Literature"

  • Chemical News

    CDK Inhibitors: Purchase With Caution

    Cyclin-dependent kinase (CDKs) have been drug targets for quite a while now. There are 20 different ones, and they help to regulate a whole list of important functions, particularly involving the cell cycle (which has made them of great interest in oncology research). There are three approved drugs in the area so far: Kisqali (ribociclib)… Read More
  • The Scientific Literature

    Write a Paper. Write a Paper. Write Another Paper.

    Time is short for blogging today, but I wanted to take a moment to point out people for whom time for writing things up is (apparently) never, ever short. This is a study on prolific authorship, and the high end of that cohort is pretty terrifying. At least 9,000 authors have been on 72 papers… Read More
  • The Scientific Literature

    Open Access With A Vengeance

    Here’s something to keep an eye on: eleven of the largest national research funding agencies in Europe have announced a plan to require open-access publication of papers arising from their grants. The plan is that by 2020, all such work must be published in compliant open-access journals or on compliant open-access platforms. There are quite… Read More
  • The Dark Side

    India Tries to Deal With Predatory Publishers

    There’s more activity on the predatory journal front. A large investigation reported recently that the number of papers put out by the five largest publishers in this category has tripled since 2015, so there’s clearly an expanding market for such “services”. Among the elite (by which I mean the top layer of this pond scum) Read More
  • Inorganic Chemistry

    A Room Temperature Superconductor? Well. . .

    Superconductivity is one of those places where chemistry and physics cross paths. That’s especially true as people search for higher-temperature materials, because that seems to involve more and more complex synthesis and characterization of the results. Very tiny changes in conditions or starting materials can make for huge differences in th… Read More
  • In Silico

    Machine Learning’s Awkward Era

    The whole machine learning field has a huge amount to offer chemistry, medicinal chemistry, and biomedical science in general. I don’t think that anyone seriously disputes that part – the arguing starts when you ask when this promise might be realized. In the abstract, the idea of tireless, relentless analysis of the huge piles of… Read More
  • Natural Products

    A Slow, Slow Retraction

    Some readers may recall this post from 2015, which details problems with a natural product isolation paper in PLOS ONE. The compound, named Xinghaiamine A by the authors, was. . .well, let’s say extremely unlikely, and I think anyone who looks at the structure in that earlier post will agree. And that spans several levels… Read More
  • The Dark Side

    How Many Doctored Papers Are Out There?

    Just how much crap is out there in the scientific literature? “Quite a bit” comes the answer from anyone with real experience of it, but that’s not too quantitative. Here, though is an analysis of one (perfectly respectable) journal of its own output, and the results are. . .well, they range from “pretty bad” to… Read More
  • General Scientific News

    Science Reform in China

    There have been all sorts of scientific scandals involving faked journal articles, faked peer reviews, duplicated papers and figures, etc. over the last few years. It’s been a running battle: our current technologies allow for these things to be done more easily, but caught more easily as well. And a pretty significant share of these… Read More
  • The Scientific Literature

    Predation

    “Beall’s List”, as a way to keep track of predatory publishers, has been officially offline for some time now. Jeffrey Beall himself has said that it was taken down under “intense pressure” from his employer (the University of Colorado at Denver), although his employer says no, not at all, this was his personal decisio… Read More
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