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  • How Do You Know When to Stop?

    Qetzal makes a good point in the comments to the previous post: “fail quickly” is fine, but when are you sure that you’ve failed? It’s a… Read More
  • An Era Begins

    The big news today was the Thursday release of two papers, one from Science and one from the NEJM, from two teams who have done something that we in the drug in… Read More
  • One Of Us Is Hallucinating

    I’ve been involved in the comments section of another blog, a discussion of pharmaceutical prices which took off from the posts over here. Things have tak… Read More
  • All Fixed Up

    Time to revisit a long-standing topic. You may well have noticed the news items about the FDA’s new programs to crack down on prescription drug counterfei… Read More
  • Easterbrook Post Updated

    I wanted to point out the update at the end of the “Cold Equations” post below, in case anyone’s interested. There’s been a lot of mail… Read More
  • The Cold Equations

    Here’s a question for the folks at The New Republic: are you really sure that Gregg Easterbrook’s blog is a good idea? Just checking. He’s alr… Read More
  • Ricin Redux

    Now that the suspected ricin in the Senate (and White House?) has been confirmed, I thought I’d repost a version of something I wrote about a year ago on… Read More
  • Deal Me In

    The inventor of the blue-light diode, Shuji Nakamura, has been fighting for some years now for a bigger piece of the profits from his invention. Since his origi… Read More
  • Not in My European Back Yard

    I wanted to mention another thing about Sanofi-Synthelabo’s bid for Aventis. I hope that the French government keeps in mind, as they promote this deal, t… Read More
  • Secretin

    Secretin is a signaling peptide that stimulates the pancreas. It kicks in when food is consumed, causing the pancreas to secrete its mixture of digestive enzyme… Read More
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