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Posts tagged with "Who Discovers and Why"

  • Drug Development

    Grit And Giving Up, Experience and Ignorance

    It seems to be a fairly slow news day in biopharma – not always such a bad thing – so I wanted to bring up a general drug discovery question. Unfortunately, I’m not sure it has a good answer. What is the proper balance between perseverance and pragmatism – in other words, how do you… Read More
  • Business and Markets

    Startups In Other Parts of the Map

    I read this piece on venture capital with some interest, because it addresses a topic I’ve thought about (and which has come up several times on this blog): where startup companies get funded. It’s been clear for some time now that that the biopharma industry has been concentrating more and more in the San Francisco… Read More
  • Academia (vs. Industry)

    A Professor’s View On Drug Company Collaborations

    My post the other day on Phil Baran’s public-private funding ideas brought in a lot of comment. As usual, I encourage a look a the comments section if you’re interested in the topic, or any topic that comes up around here – a lot of people who know whereof they speak show up. But I… Read More
  • Academia (vs. Industry)

    Don’t Wait For the Public Sector

    If you haven’t seen this speech by Phil Baran, given at his induction into the American Academy of Arts and Sciences, it’s worth a look. His main theme is what organic chemists can learn from the business model of SpaceX, and he starts out by talking about how grant money for synthetic organic chemistry has… Read More
  • Who Discovers and Why

    The Story Behind the Story Behind the Story

    I enjoyed this article at FiveThirtyEight, because I’ve had similar thoughts over the years myself. There are layers of knowledge about many topics, and it can be hard to be sure what layer you’ve made it do, and whether there’s another one underneath you yet. The first example in the piece is the spinach-has-a-lot-of-iron idea… Read More
  • Book Recommendations

    Realizing That There Was Such a Thing as Science

    I’ve been enjoying this book, The Invention of Science by David Wootton, which was just published in the US back in December. It’s a history of the beginnings of the scientific revolution back in the 1500s and 1600s, and it takes a lot of issues with how that history has been told by some other authors. Read More
  • Business and Markets

    An Old Problem at Verily

    Stat has a very interesting report on what’s going on at one of Google’s biomedical companies, Verily Life Sciences. They get right down to it in the opening: Google’s brash attempt to revolutionize medicine as it did the Internet is facing turbulence, and many leaders who launched its life sciences startup have quit, STAT has found. Read More
  • Business and Markets

    The Management Hat

    On this anniversary, I wanted to point back to an older post here: Roger Boisjoly and the Management Hat. He tried, repeatedly, to keep the Challenger disaster from happening, but upper management decided that there were more important things to worry about: goals, timelines. Never forget. Read More
  • Academia (vs. Industry)

    Technology and Funding: Myths and Alternate Worlds

    Science writer Matt Ridley had an interesting (but somewhat odd) column over the weekend in the Wall Street Journal. Titled “The Myth of Basic Science”, it maintains that “technological innovation has a momentum of its own”, and that basic research doesn’t really drive it. I think that my brain must be about ninety deg… Read More
  • Biological News

    Reductionism Pays My Mortgage

    Reductionism has been a powerful tool for a long time now, and it’s not going away any time soon. There, that should be enough of a 50,000-foot opening! The idea that you can understand a system by taking it apart and looking at the pieces doesn’t always work out, but it still seems to be… Read More