• February 20, 2002

    Giordano Bruno

    I missed a chance yesterday to note an anniversary. Giordano Bruno was something of a crank, not normally the sort of person I’d be commemorating. But in his time, it didn’t take very much to be considered either of those, or worse, and we have to make allowances. He was headstrong. We can see now… Read More
  • February 18, 2002

    A Couple of Days Off

    I won’t be posting for another day or two; I’m taking tomorrow off from the Wonder Drug Factory and heading out with the family. My chemistry can get along without me just fine, and the people that report to me will most likely be even more productive without me around. Leaving the lab for a… Read More
  • February 14, 2002

  • February 7, 2002

    The Latest Thing

    The pharmaceutical industry is overdue for another crazy idea. Go back to the mid/late 1980s, for example, and you hit the first swell of computer-aided “rational” drug design. It’s hard to remember, but the hype was that random screening and old-fashioned analog synthesis were both dead. Shooting arrows blindly, hoping to hit you… Read More
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