Biocentury has a roundup of reactions to the recent human CRISPR paper:
There’s no dispute that because the technology is in its infancy, much more work needs to be done to establish its safety. Stakeholders also agree that no experiments should be done, at least for now, in clinical programs that would involve modifying germline DNA and creating gene-edited embryos.
However one camp argues that research to understand the technology better and establish its safety in human cells should be permitted under appropriate regulatory controls. That means gene editing would be performed on human germline cells, but that any products would be discarded. Advocates for that position believe it’s worth considering whether there are therapeutic situations where using gene editing might be beneficial.
The other school of thought is that there will never be a justifiable use related to human germline cells, and that no experiments should be done for either research or clinical applications. The argument is not just that it’s a slippery slope from establishing safety and methods for well-meant therapeutic uses to providing a roadmap for eugenics.
Over the whole discussion, though, seems to be an air of “Well, someone’s going to be doing it; it’s just a matter of when”. That’s how I see it, and that makes the job how to have it happen in the least crazy way possible.