Derek Lowe's commentary on drug discovery and the pharma industry. An editorially independent blog from the publishers of Science Translational Medicine. All content is Derek’s own, and he does not in any way speak for his employer.
The weather here in the Boston area is doing the full Christmas/Winter experience, with sleet and freezing rain followed up a couple of days later by seven inches of snow. And over the next few days the temperature is dropping day by day, heading down below zero (Fahrenheit!) on Thursday. So it’s clearly time for… Read More
So it’s heading into the end-of-the-year time, and I myself am taking off work until January. Blogging around here will be somewhat irregular, and will feature more recipe lab preps than usual. If there’s any big news, I’ll certainly post about it, but otherwise, some days there will be stuff here and some days there… Read More
This is one that I tried out this year for Thanksgiving, and it seemed to go over well. It’s a version of a recipe published by Bon Appetit, stripped of some frou-frou and with the preparation modified a bit. You’ll need cranberries, eggs, limes, sugar, butter (room temperature), and some sort of crust material (see… Read More
Work and home have left me little time for blogging today. Topics coming up in the next few days, though, include lessons about working with bigger-than-normal drug molecules, some insights on covalent compounds in living systems, chemistry in Flatland, and more. See everyone on Monday! Read More
I’ll be taking a break this week, up through next Monday, while doing some traveling with the family. With any luck, we’ll see the total eclipse a week from now, unless the usual amateur astronomer’s luck is working, in which case we’ll see hail the size of canned hams coming down instead. So there’s that… Read More
Since many people have checked in with me to see how things have been going, I wanted to mention that today is, in fact, my first day on my new job. I’m very happy to report this, both for the obvious reasons, and because the research I’ll be doing looks to be very interesting and complex, and… Read More
Some behind-the-scenes trouble with WordPress left me unable to log in to the site until now, but I wanted to mention that at this very moment, I’m doing an “Ask Me Anything” on Reddit’s Science section. Drop by and see how quickly I can keep up the typing! Read More
I wanted to let people know that posting will resume here this coming Wednesday – I’ll be traveling, and I probably won’t have time to put up any entries. If something big happens, I’m sure I’ll work something in, but otherwise, I’ll see everyone on the 19th! In the interim, I’d be glad to hear… Read More
I wanted to mention something going on back behind the curtain here, namely that my employer and I have parted ways. A number of my other colleagues are going through similar experiences as things reorganize, but for my own part, I’m looking into several new opportunities in the Boston/Cambridge area. And that’s just the place… Read More
I’ve been thinking about a recipe or two to post here, but I’ve already covered several favorites over the years (do a Google search starting with the phrase site:blogs.sciencemag.org/pipeline and then the word recipe; that’ll call them up). They get used frequently around Pipeline HQ here – the gingersnap cookies were made… Read More
