Skip to main content
Menu

Posts tagged with "Business and Markets"

  • Business and Markets

    The Last of Stemcentrx

    The final implosion of the Stemcentrx deal is worth a note, although I said a lot of what I have to say about it back in December. I want to especially emphasize two points I made back then – first, that the failure of this whole acquisition is different only in degree, and not in… Read More
  • Business and Markets

    Startups And Their Publications

    How much does scientific publication matter? For once, we’re not going to be talking about its role in academia (partly because it obviously means quite a bit there!) No, how much does it matter in industry? Specifically, at highly valued biomedical startups? That’s the subject of this new paper by John Ioannides and co-authors, and… Read More
  • Biological News

    Virus-Only Gene Editing, Or Not?

    I wrote here about a new company (Homology Medicine) that claimed to have a viral method for gene editing that did not involve any sort of double-strand DNA breaking enzyme (as you need during the CRISPR, TALENs, or zinc-finger nuclease methods). That’s a pretty interesting claim, because double-strand breaks (DSBs) are powerful but can be… Read More
  • Business and Markets

    Revenues From New Drugs – And Thoughts on Chance

    Here’s an interesting analysis of the industry from IDEA Pharma, via Endpoints. They’re looking at the revenues from the more recent drugs in the pipeline (approved in the last five years) and comparing that to each company’s total R&D spending. The list is all Big Pharma – the cutoff is companies that have at least… Read More
  • Business and Markets

    AbbVie, Allergan, Ugh

    News broke yesterday morning (first at the Wall Street Journal, I believe) that Abbvie has agreed to acquire Allergan. This is one of the larger pharma mergers of recent years, and regular readers of this site will have a pretty good idea of the sigh and roll of the eyes with which I greet it. Read More
  • Academia (vs. Industry)

    Innovation, at Universities and in Industry

    Some thoughts this morning on universities and industry and their contributions to research – and for once, this isn’t going to be another long screed on drug research in particular. No, I’m particularly talking about what each of these brings to R&D in general, and about the places (both conceptual and physical) where they se… Read More
  • Alzheimer's Disease

    A Missed Alzheimer’s Opportunity? Not So Much

    The Washington Post made quite a splash with this story about Pfizer, Enbrel (etanercept), and Alzheimer’s disease. There’s already been a lot of comment about it yesterday on Twitter and in some other venues, but I thought it might be useful to try to sum things up in an easily accessible place. Here we go: Read More
  • Biological News

    Antibody Design, Publicly Challenged

    Comes now some rather disturbing news in the antibody field. These things are extremely important, both as therapeutics and as research reagents, and developing them for either purpose is no stroll down the garden walk. There are a number of techniques for raising and producing antibodies (see that first link), but they all have their… Read More
  • Business and Markets

    Catalyst and Jacobus and LEMS: The Latest Chapter

    I last wrote about the situation with Catalyst Pharmaceuticals here last December when Firdapse, their drug for Lambert-Eaton myasthenic syndrome, was approved by the FDA. If you know the story, though (or follow the links in that post) you’ll see that referring to it as “their drug” is a rather legalistic way of looking at thing… Read More
  • Business and Markets

    The Going Rates, 2019 Edition

    I did a post a few years ago that was a sort of informal salary survey for biopharma folks (I asked initially about the Boston/Cambridge area, but responses came in from many other places as well). I’ve had a recent request for an update, and I think it would make an interesting comparison.. So break… Read More
123...