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Posts tagged with "Drug Industry History"

  • Business and Markets

    CafePharma Will Now Approach The Bench

    Here’s an interesting situation for you: according to IguanaBio, a shareholder lawsuit over the failed Vytorin ENHANCE clinical trial (that’s caused Schering-Plough and Merck so much grief) is going to use posts on CafePharma as evidence. That will be worth watching. CafePharma’s message boards have been described (accurately, I&# Read More
  • Business and Markets

    Akt and Mek, But Not PDQ

    Well, the ASCO meeting has been roaring along, with dozens of press releases coming out. (Go to Google News and type that acronym in if you want to get the full experience). They range from the pretty-interesting to the despair-inducing, but one bit of news struck me as particularly worth noting. That’s the early-stage deal… Read More
  • Drug Development

    The NIH Takes the Plunge

    The NIH has announced that they’re going to start up a preclinical drug discovery effort to address rare diseases. I find this interesting for several reasons. For one thing, it’s worth a try for conditions where no company has seen a way to fund research, and there are quite a few of them. Treating rare… Read More
  • Business and Markets

    San Francisco Biotech: Holding Up, or Not?

    I’ve got a piece coming up today at The Atlantic Monthly‘s business site on the state of the biotech industry out in the Bay Area. Since the Genentech takeover fight broke out, a persistent theme in the comments here (and in e-mail that I’ve received) has been how well the industry is holding up out… Read More
  • Drug Industry History

    Book Review Department

    For those who are interested, I have a review up at Nature Biotechnology of Reasonable Rx: Solving the Drug Price Crisis, a book that proposes an. . .interesting solution for reworking the drug industry. And as Fate would have it, I also have a review in the latest issue of Nature Chemistry of Drug Truths: Read More
  • Cardiovascular Disease

    Farewell to ACAT, and to Lots of Time and Money, Too

    Back when I joined the first drug company I ever worked for, the group in the lab next door was working on an enzyme called ACAT, acyl CoA:cholesterol acyltranferase. It’s the main producer of cholesterol esters in cells, and is especially known to be active in the production of foam cells in atherosclerosis. It had… Read More
  • Biological News

    Genes to Diseases: Hard Work, You Say?

    So I see that the headlines are that it’s proving difficult to relate gene sequences to specific diseases. (Here’s the NEJM, free full-text). I can tell you that the reaction around the drug industry to this news is a weary roll of the eyes and a muttered “Ya don’t say. . .” That’s because we… Read More
  • Drug Industry History

    Who They?

    I try to keep up with the drug-industry news in general, so once in a while I just hop over to Google News and type “pharmaceutical” into the search box. That generally gets me a barrage of press releases, lucky me, and this morning was no different. But what struck me was that basically the… Read More
  • Drug Industry History

    Scientists Running Your Drug Company?

    There’s an interesting article that showed up in the Financial Times about the leadership of drug companies. Specifically, the number of them that are run by scientists (always lower than you would have thought) is dropping even further. “Only one large western pharmaceutical company will be run by a scientist (John Lechleiter of Lilly) Read More
  • Drug Development

    The Mechanical Chemist?

    We use a lot of automated equipment in the drug discovery business. There’s an awful lot of grunt work involved, and in many cases a robot arm is better suited to the task – transferring solutions, especially repetitive transfers of large numbers of samples, is the classic example. High-throughput screening would just not be possible… Read More