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Posts tagged with "Life in the Drug Labs"

  • Life in the Drug Labs

    Wastes of Time (And Not)

    Couldn’t blog on the train this morning, and pushing back the frontiers of science has occupied me since then. And news is scarce, as it often seems to be in mid-August. So I’ll throw out a dual question to the readership, building on one that got started in the comments section the other day. A. Read More
  • Life in the Drug Labs

    Laboratory Weather Conditions

    It’s hot out there in Boston today – hot the way it gets in Arkansas or Georgia, but not too often up here. I, of course, will be hanging out in air-conditioned labs and offices, with no need to stick my head outside, but even so, this would not be a good day to run… Read More
  • Life in the Drug Labs

    Solo Chemistry

    Many US readers are off today for President’s Day – I nearly did what I actually did do a few years ago, and forget about the holiday entirely. I came in to work that year, noted that there was no one around, and realized that you know, this was one of those holiday things, wasn’t… Read More
  • Business and Markets

    The Management Hat

    On this anniversary, I wanted to point back to an older post here: Roger Boisjoly and the Management Hat. He tried, repeatedly, to keep the Challenger disaster from happening, but upper management decided that there were more important things to worry about: goals, timelines. Never forget. Read More
  • Life in the Drug Labs

    Descents Into the Instrumentation Inferno

    Things have been exceptionally busy around here, thus no blog post until nearly lunchtime! It’s that darn real-world lab work again, interfering with the important things in life. In this case, I’ve been wrestling with a recalcitrant piece of equipment that’s crucial to gathering data on a project I have going, and it has been… Read More
  • Chemical News

    Boring! Or: The Medicinal Chemist’s Toolkit

    There’s a new paper out on a topic that is of great interest for medicinal chemists: what sort of chemistry is it that we’re spending all our time doing? It’s a study of the literature from 1984 to 2014, analyzed by reaction type and other factors, and here’s the take-home: “. . .of the current… Read More
  • Life in the Drug Labs

    There’s Something A Bit Off With This

    When we last checked in with Bristol-Myers Squibb, employees at their (closing) Wallingford site were being given “discovery evolution interviews” to learn their fates. Now there’s something else to report – this time in plain English, fortunately, although just as bizarre. Apparently the company is doing an internal promoti… Read More
  • Life in the Drug Labs

    Doubleplusgood CorporateSpeak

    It was back in late June that Bristol Myers Squibb announced that they were closing their Wallingford, CT site and relocating employees. Some employees. You might have thought that people would know their fate by now, but you’d be mistaken. Many are just finding out if they’re going to be able to apply for a… Read More
  • Drug Industry History

    That One Big Answer

    This post by Wavefunction on the foxes-and-hedgehogs split in drug discovery is well worth reading. You may recall, via Isaiah Berlin and Archilochus, that a fox knows many things, while a hedgehog knows one big thing. Here’s how that can apply to the drug R&D business: Now drug discovery should be the poster boy for… Read More
  • Life in the Drug Labs

    No Water, No Problem

    I have some colleagues who are evaluating these “no flowing water” condensers for reactions. Anyone out there have any experience with them? It’s for sure that there have been a lot of lab floods over the years from condenser hoses that pop off, and the expense of all that water can be a problem, too. Read More