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Posts tagged with "Who Discovers and Why"

  • The Scientific Literature

    Read, And Read the Odd Stuff

    This article gets across a truth that many people have heard as a piece of advice, but find hard to follow: read the scientific literature widely. Perhaps the bigger question is why I make the effort. The short answer is that I read widely to prepare myself for whatever might come along in the lab. Read More
  • In Silico

    The Flightosome

    I got this diagram from Arjun Raj‘s Twitter feed, and I think I enjoy it a bit more every time I see it. Some of that is because it’s a big part of what I was trying to get across in this column, but I think that the sketch does a more thorough job of… Read More
  • Blog Housekeeping

    End of a Year

    This is my last workday of the year – I’ll be posting occasionally into the new year, but some of those will be recipes (as is traditional around here). If there’s any big scientific news, though, I’ll rouse myself and talk about it. Today I’m just heading into the lab to get things wrapped up… Read More
  • Business and Markets

    Out of Ideas?

    The Wall Street Journal came out with a series of articles on innovation in the US, and the biopharma industry features quite a bit in them. The lead one is an overview, with the theme of “The US economy’s hidden problem is that we’re out of big ideas”, and there’s another one specifically on Sanofi… Read More
  • Graduate School

    Getting Going

    I’ve had a chance recently to talk to some people who are heading off to chemistry grad school in the fall, which brought back memories of when I did that a mere thirty-three years ago. A lot has changed over that time, but there are some very important things that haven’t. One of the most… Read More
  • Drug Industry History

    Company Time For Your Own Ideas, Or Not?

    Over the years, at many R&D-driven companies, there have been official/unofficial policies that researchers could spend some percent of their time pursuing their own ideas, versus their official projects and goals. You hear different figures, especially when it comes to past glories, but there are definitely companies that have made this a stat… Read More
  • Who Discovers and Why

    No Scientific Method, They Say

    Several people have sent this article along, and since there’s not a lot of news so far today, I thought I’d go into it a bit. The title is eye-catching: “There Is No Scientific Method”, but that contention is probably the least objectionable part of the whole thing. Physicist Chad Orzel thought so – his problem… Read More
  • Drug Development

    Grit And Giving Up, Experience and Ignorance

    It seems to be a fairly slow news day in biopharma – not always such a bad thing – so I wanted to bring up a general drug discovery question. Unfortunately, I’m not sure it has a good answer. What is the proper balance between perseverance and pragmatism – in other words, how do you… Read More
  • Business and Markets

    Startups In Other Parts of the Map

    I read this piece on venture capital with some interest, because it addresses a topic I’ve thought about (and which has come up several times on this blog): where startup companies get funded. It’s been clear for some time now that that the biopharma industry has been concentrating more and more in the San Francisco… Read More
  • Academia (vs. Industry)

    A Professor’s View On Drug Company Collaborations

    My post the other day on Phil Baran’s public-private funding ideas brought in a lot of comment. As usual, I encourage a look a the comments section if you’re interested in the topic, or any topic that comes up around here – a lot of people who know whereof they speak show up. But I… Read More